Best Cannabis Strains for Pain Relief (2025 Guide)

Pain is personal—and cannabis offers personalized relief. Whether you’re battling chronic back pain, muscle tension, or migraines, the right cannabis strains for pain relief can make all the difference.
In this guide, you’ll learn:
- How cannabis interacts with pain pathways
- Why terpenes and strain type matter
- The best Hypno Seeds strains to grow for pain relief
TL;DR – Best Cannabis Strains for Pain
Strain | THC % | Best For | Effects | Flower Time |
---|---|---|---|---|
GMO | 28% | Chronic pain, back aches | Sedating, euphoric, deep | 8–10 weeks |
Northern Lights | 18% | Sleep & nerve pain | Soothing, heavy, relaxing | 7–9 weeks |
Ice Cream Cake | 25% | Muscle tension & cramps | Calming, lightly sedative | 8–10 weeks |
Purple Punch | 20% | Migraines & inflammation | Uplifting, tingly, mellow | 9–10 weeks |
Jealousy | 20% | Joint pain & anxiety | Balanced, relaxing, joyful | 9–10 weeks |
How Cannabis Eases Pain
Cannabis works by interacting with the endocannabinoid system (ECS)—a built-in network that regulates pain, mood, inflammation, and sleep. Key compounds like THC and CBD can:
- Decrease inflammation in muscles and joints
- Block pain receptors in the brain
- Improve relaxation and sleep, speeding recovery
A NIH-reviewed study (source) confirms that cannabis is especially effective for neuropathic and chronic pain.
Hypno Seeds’ Top Picks for Pain Relief
GMO – 28% THC
GMO’s knockout potency and diesel-like funk bring strong sedation and full-body relief. Perfect for night use or chronic pain flares.
👉 Grow GMO Seeds – Indoor: 1.3–1.6 oz/ft² | Outdoor: 20–30 oz/plant
Northern Lights – 18% THC
Don’t be fooled by the moderate THC—this iconic indica offers deep body relaxation and nerve-calming properties.
👉 Northern Lights Seeds – Indoor: 1.5–1.6 oz/ft² | Outdoor: 18–22 oz/plant
Ice Cream Cake – 25% THC
Its sweet profile masks powerful effects that help melt muscle spasms, joint pain, and stress.
👉 Ice Cream Cake Seeds – Indoor: 1.4–1.5 oz/ft² | Outdoor: 20–30 oz/plant
Purple Punch – 20% THC
Excellent for migraines and menstrual discomfort, this hybrid soothes both head and body without knocking you out.
👉 Purple Punch Seeds – Indoor: 1.8–2.1 oz/ft² | Outdoor: 16–22 oz/plant
Jealousy – 20% THC
Great for daytime use, Jealousy offers anti-inflammatory and relaxing benefits without heavy sedation.
👉 Jealousy Seeds – Indoor: 1.3–1.5 oz/ft² | Outdoor: 16–18 oz/plant
Best Times to Use These Strains
Time of Day | Suggested Strain | Why |
---|---|---|
Morning | Jealousy | Light pain relief, low fog |
Afternoon | Purple Punch | Mild relaxation, calm focus |
Evening | Ice Cream Cake | Relieves tension, boosts rest |
Night | GMO or Northern Lights | Deep sedation, sleep aid |
Related Resources on Hypno Seeds
- Indica Seeds Collection – Known for calming, body-focused effects
- High THC Strains – If you need a stronger hit for relief
- Organic Nutrients Guide – Grow healthy plants with fewer toxins
Final Thoughts: Natural Pain Relief, Grown by You
Whether you’re dealing with daily aches or long-term discomfort, cannabis strains for pain relief can help you regain control without harsh meds. The strains above offer different types of relief for different kinds of pain—so choose what fits your body best.
Want real relief? Start by growing it.
Browse the Hypno Seeds shop for premium genetics that work hard—just like you do.