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Best Cannabis Strains for Pain Relief (2025 Guide)

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Pain is personal—and cannabis offers personalized relief. Whether you’re battling chronic back pain, muscle tension, or migraines, the right cannabis strains for pain relief can make all the difference.

In this guide, you’ll learn:

  • How cannabis interacts with pain pathways
  • Why terpenes and strain type matter
  • The best Hypno Seeds strains to grow for pain relief

TL;DR – Best Cannabis Strains for Pain

StrainTHC %Best ForEffectsFlower Time
GMO28%Chronic pain, back achesSedating, euphoric, deep8–10 weeks
Northern Lights18%Sleep & nerve painSoothing, heavy, relaxing7–9 weeks
Ice Cream Cake25%Muscle tension & crampsCalming, lightly sedative8–10 weeks
Purple Punch20%Migraines & inflammationUplifting, tingly, mellow9–10 weeks
Jealousy20%Joint pain & anxietyBalanced, relaxing, joyful9–10 weeks

How Cannabis Eases Pain

Cannabis works by interacting with the endocannabinoid system (ECS)—a built-in network that regulates pain, mood, inflammation, and sleep. Key compounds like THC and CBD can:

  • Decrease inflammation in muscles and joints
  • Block pain receptors in the brain
  • Improve relaxation and sleep, speeding recovery

NIH-reviewed study (source) confirms that cannabis is especially effective for neuropathic and chronic pain.

Hypno Seeds’ Top Picks for Pain Relief

GMO – 28% THC

GMO’s knockout potency and diesel-like funk bring strong sedation and full-body relief. Perfect for night use or chronic pain flares.
👉 Grow GMO Seeds – Indoor: 1.3–1.6 oz/ft² | Outdoor: 20–30 oz/plant

Northern Lights – 18% THC

Don’t be fooled by the moderate THC—this iconic indica offers deep body relaxation and nerve-calming properties.
👉 Northern Lights Seeds – Indoor: 1.5–1.6 oz/ft² | Outdoor: 18–22 oz/plant

Ice Cream Cake – 25% THC

Its sweet profile masks powerful effects that help melt muscle spasms, joint pain, and stress.
👉 Ice Cream Cake Seeds – Indoor: 1.4–1.5 oz/ft² | Outdoor: 20–30 oz/plant

Purple Punch – 20% THC

Excellent for migraines and menstrual discomfort, this hybrid soothes both head and body without knocking you out.
👉 Purple Punch Seeds – Indoor: 1.8–2.1 oz/ft² | Outdoor: 16–22 oz/plant

Jealousy – 20% THC

Great for daytime use, Jealousy offers anti-inflammatory and relaxing benefits without heavy sedation.
👉 Jealousy Seeds – Indoor: 1.3–1.5 oz/ft² | Outdoor: 16–18 oz/plant

Best Times to Use These Strains

Time of DaySuggested StrainWhy
MorningJealousyLight pain relief, low fog
AfternoonPurple PunchMild relaxation, calm focus
EveningIce Cream CakeRelieves tension, boosts rest
NightGMO or Northern LightsDeep sedation, sleep aid

Related Resources on Hypno Seeds

Final Thoughts: Natural Pain Relief, Grown by You

Whether you’re dealing with daily aches or long-term discomfort, cannabis strains for pain relief can help you regain control without harsh meds. The strains above offer different types of relief for different kinds of pain—so choose what fits your body best.

Want real relief? Start by growing it.
Browse the Hypno Seeds shop for premium genetics that work hard—just like you do.

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